Lawrence Rothblat

Title:
Professor, Cognitive Neuroscience
Office:
Room 312
Address: 2125 G St NW
Washington, District Of Columbia
20052
Phone: 202-994-6809
Email:
[email protected]

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Current Research

My laboratory is using genetically engineered mice to study how gene mutations alone, or in combination with environmental factors, can alter cortical circuitry and lead to the behavioral symptoms that characterize autism and related neurodevelopmental disorders.

Education

Ph.D. 1968, University of Connecticut

Publications

Meechan, D.W., Rutz, H.L.H., Fralish, M.S., Maynard, T.M., Rothblat, L.A. and La Mantia, A.-S. (2015) Cognitive ability is associated with altered medial frontal cortical circuits in the LgDel mouse model of 22q11DS mouse model, Cerebral Cortex, 25(5):1143-51.

Meechan, D.W, Maynard, T.M., Fernandez, A., Karpinski, B.A., Rothblat, L.A. and LaMantia, A.-S., (2015).  Modeling a model: Mouse genetics, 22q11.2 Deletion Syndrome, and disorders of cortical circuit development. Progress in Neurobiology, 130:1-28.

Brigman, J.L. &  Rothblat, L.A. (2008).  Stimulus specific deficit on visual reversal learning after lesions of medial prefrontal cortex in the mouse. Behavioural Brain Research, 187, 405-410.

Brigman, J.L., Padukiewicz, K.E., Sutherland, M.L. & Rothblat, L.A. (2006). Executive functions in the heterozygous Reeler mouse model of schizophrenia. Behavioral Neuroscience, 120(4), 984-988.

Brigman, J.L., Bussey, T.J., Saksida, L.M., & Rothblat, L.A. (2005). Discrimination of multidimensional visual stimuli by mice:Intra- and extradimensional shifts. Behavioral Neuroscience, 119(3), 839-842.

Bussey, T.J., Saksida, L.M., & Rothblat, L.A. (2001). Discrimination of computer-graphic stimuli by mice:A method for the behavioral characterization of transgenic and gene-knockout models.  Behavioral Neuroscience, 115(4), 957-960.